The newly discovered corona virus hCoV-EMC (human corona virus-Erasmus Medical Center) which have been causing severe, sometimes fatal lower respiratory infections, is using a protein CD26, which is also called dipeptidyl-peptidease 4, to gain entry to cells. The virus is highly similar in terms of sequence to one found in bats. This paper shows expression of the human and bat CD26 receptor in nonsensitive cells, enables infection. This suggests a therapeutic target.
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Adam Kallel Ph. D.
Our CSO sounds off about drug discovery, computational chemistry and history